This will surely suffice for many horror fans -- it displays the competence of the big-budget apocalyptic thriller, carefully trotting out the (stock) characters, carefully teasing and deploying the (stock) scenario, with just enough tweaking to suggest innovation without annoying the base. I like the high-concept reframing of vampirism, but frankly at 150 pages I was still muddling through the set-up. That's fine, if you've got some wit, even in merely reiterating stock characters. (See any number of great C-grade monster films, particularly the lovely
Tremors, say, or del Toro's own fine
Blade II.) But these characters could be simply checked off (iconoclastic family-man-torn-by-vocational-passion hero, check), and the actual, extensive explication of each then became an exercise in redundancy. And, as many reviewers note, in the film adaptation (sure to come?) this stuff will be done with a far more ruthless efficiency . . . so, I will wait.
If you want a great new vampire story, go read and/or see
Let The Right One In.